During the 1970s, Slobodkina struggled to cope with a number of personal tragedies.
While still grieving the death of her her second husband, William Urquhart, who passed away in 1963 only three years after their marriage, Slobodkina lost her brother, a favorite cousin, her aunt, and long-time friends George L.K. Morris, Suzy Frelinghuysen, and Alice Mason. To cope with a deep and mounting depression, Slobodkina began writing her Notes for A Biographer – an 1100-page autobiography – in 1970.
In 1978, Slobodkina moved to Hallandale, Florida, with her mother and her sister Tamara. She had a one-person show in Florida at the Hollywood Art Museum the next year.